Add to favorite
Subscribe to our Newsletters Subscribe to our Newsletters Get Daily Updates RSS

Artificial Skin to Treat Severe Burns
February 3, 2010 20:43

Extensive burns are a very difficult thing to cure – the larger is damaged area, the harder it is to cover the wound. However, Russian medics recently saved two people, 98% of whose skin was burnt.

Russian cytologists are professionals in cultivating various cells, including human cells, and studying their properties. Department of Cell Cultures hosts a bank of dermal fibroblasts, stored in liquid nitrogen – 196 degrees below zero Centigrade. Ten years ago military medics came to cytologists and offered a challenge – to grow cells, which would be able to replace skin, when 30% of it and even more is destroyed by fire. Scientists thought it would be interesting and learnt to grow such cells and to make cell products (composites of cells and their protein metabolites), which are essential for injured skin healing. These cell products, which are not rejected by patient’s immune system, serve as a basis for growing of patient’s own skin. There are two types of such cell products – first one is derma equivalent and works like a foundation, hosting fibroblasts in collagen gel. These immobilized fibroblasts produce proteins and create framework for the second type of cells, keratinocytes, which comprise epidermis, upper skin layer, in other words. Bottom layer serves like a regulator, controlling division, movements and functioning of keratinocytes, Russian cytologists explain.



During investigation scientists found out an interesting fact – their creation helps not only patients with severe burns, but also those, who suffer from open trophic ulcers, fistulas, bed sores and any other serious skin defects.

“Artificial skin” from St Petersburg’s Institute of Cytology (Russian Academy of Sciences) has successfully passed clinical trials in Military Medical Academy, Burdenko hospital, science and research institute of emergency. Of course, before clinical trials, skin alternative has passed long-term compulsory technical and toxicological tests in Moscow Institute of Transplantology and Artificial Organs, which is the part of the Russian Ministry of Health. In 2002 the innovation has finally got its first official document – it was recommended for serial production and introduction into medical practice, as well as for registration as a medical purpose item as “Multilayer formation of keratinocytes – sterile epidermis analogue, sutable for transplantation over burnt surfaces”.

Four years ago – in 2006 – researchers received another official document from RosZdravNadzor (governmental structure, which monitors health institutions), which is a registration certificate on “dermal equivalent”. All mentioned documents allow scientists to legally supply their innovation to various medical institutions.

Researchers from Department of Cell Cultures also developed a special thermally controlled container for transportation of cell products. Scientists also offer courses for medics, where they teach how to deal with alternative skin and how to make it become part of a patient and help his wound to cure.

Source: Vechnaya molodost'

Kizilova Anna

Tags: Russian Scientists     

Next Previous

You might also find interesting:

Working Rats New Neutron Detector has been Created Russian Biophysicist to Personally Test his Rejuvenation Technology Grab Antimatter and Hold it Nanotechnologies Against Cancer

Comment on our site

RSS   twitter      submit

Active Travel  Sberbank-CIB  Russian holidays  St. Petersburg  Russian business  VTB  Russian scientists  Installations  Moscow  Mercedes-Benz Fashion Week Russia  Balakhna  Russian Cinema Week  AquaJazz  Borislav Brondukov  fashion designer  Republic of Korea  Russian tourism  Valeri Zolotukhin  Russian economy  economic amnesty  Kaliningrad Region  Russian academy of sciences  Republic of Bashkortostan  Exhibitions in Moscow  Street Art  Pyotr Rychkov  Sochi Olympic Games 2014  Kaluga Region  Tver region  Russian science  Olympus Fest  gaming in Russia  Flakon design factory  Alexander Deyneka  Moscow actions  Gregorian  Russian culture  Exhibitions in St. Petersburg  Russian Cinema  cosmos  Paleontology  Alexander Voytsekhovsky  child adoption in Russia  Alexander Vakhrameyev  Franz Josef Land   Solovki  Inclusive Schools  Red Square  Russian aviation  human rights 

Travel Blogs
Top Traveling Sites