Mammalian cardio-vascular system is susceptible to many diseases, the most common of which is high arterial tension. This disease usually appears, when an organism matures, and emerges when all organ systems are totally formed. It’s in the childhood, when genetic defects leading to arterial tension rise can or cannot be detected. Hypertension formation to a large extent depends on hormonal background. Child organism is very sensitive to it, and most hormones a child receives through mother’s milk.
The scientists from Novosibirsk RAMS SB Physiology Institute, RAS SB Institute of Cytology and Genetics in collaboration with Novosibirsk State Medical Academy have carried out the experiments confirming breast milk healthsome effect on hereditary hypertensives.
The physiologists had the line of HSIAH (Hereditary Stress Induced Arterial Hypertension) rats at their disposal. These rats are doomed from early childhood: adult rats have arterial tension of about 170 mm hg, while ordinary rats usually have 118 mm hg. Adult rats’ blood has high level of thyroid hormones, which lead to hypertension development. Novosibirsk scientists have transferred HSIAH newborn rats for feeding to the rats of another line with normal arterial tension. Researchers have chosen donor mothers and nursing rats according to the time of their kids’ birth – it shouldn’t have varied for more than 12 hours.
Nursing rats have nursed baby rats for 25 days, and then babies were moved to separate cages. Further experiments involved only male rats: HSIAH line rats and rats with normal arterial pressure – two control groups, and HSIAH rats nursed by a normal rat – test group.
When the rats have grown up (reached the age of six months), the researches have measured their arterial pressure, made rats’ electrocardiogram and measured the level of hormones in rats’ blood. Almost all test group rats’ parameters have mediated between equivalent parameters of HSIAH rats and normal rats. Their arterial tension was certainly lower than that of hereditary hypertensives fed by their own mothers, and balances between normal tension and hypertension.
The scientists have analyzed the obtained data and have come up with a hypothesis about factors influencing high arterial tension development. It’s possible that their theories will soon turn to the real facts, and children of hypertensives will since childhood receive correcting therapy smoothing the disease appearance.