An inflammation is a normal reaction of a healthy organism on every foreign thing. The first stage is subclinical inflammation, which appears when few foreign cells invade an organism. Such organism reactions are common – it is a very important way of immune system activity. If an organism finds too much foreign matter, then subclinical inflammation turns to clinical. Clinical inflammation may result in organism recovery or death, or it may reach the chronic stage. Chronic inflammation is a disease, which organism immune system sometimes can’t fight. During the chronic stage disease flares are followed by remission, during which the organism that has partly coped with the disease, gains strength for another flare. Various allergies, hives (pseudoallergy), chronic bronchitis, tonsillitis, periodontitis, etc – these are all chronic inflammations. These diseases, however, have some common paths that to find general way to treat patients.
 

The treatment is based on prolonged activity of subclinical inflammation system during chronic processes. For example, foreign microorganisms constantly invade the organism through bronchi epithelium and are killed by immune system without causing flares with chronic pneumonia patients. Therefore, medics suggest “similia similibus curantur” – to suppress chronic inflammation by activating a subclinical one.
 

To treat chronic inflammation processes medics usually use drugs that activate immune system, for example they recommend allergens for treating allergy. These drugs are prescribed in very small doses, which are further increased. The idea of such treatment is that doctors constantly stimulate subclinical inflammation process. But the same dose of a stimulator has a different effect on each patient and can even kill him. Thus, very careful drug dose selection and total medication control should be performed.
 

Russian and Kazakh Researches suggest safer treatment modification – dosing immunotherapy. It means treating chronic patients with immunostimulants in doses causing permanent activation of subclinical inflammation process. This method differs from a traditional one by careful dose selection, not by rule of thumb. For dose control a lignin disk is soaked in a solution of certain concentration and kept behind the cheek for an hour. An hour is enough for the drug to soak into blood. A lavage from mouth cavity is performed before and after the probe and leukocyte amount is counted. Necessary dose is calculated according the level of leukocyte migration to mouth cavity. This technique is very simple and much faster that common skin probe, which takes 24 hours to be performed. Individual selection of each drug dose allows the treatment to be more effective and eliminates almost all complications.