Add to favorite
 
123
Subscribe to our Newsletters Subscribe to our Newsletters Get Daily Updates RSS


What should First be Cured Ulcer or Nerves?
before March 9, 2006

 

Nowadays turning sick due to nerves’ malfunction is not worth a whistle. One can find ulcer, for example, which is almost impossible to cure. The question is what should be cured. Ulcer treating is useless until the patient stops being nervous, and there’s no point of treating nerves, when the stomach is ailing.
 

Altruistic fellows from Human and Animal Physiology Department of MSU Biology Faculty suggest to break this vicious circle between nerves and stomach using amylin hormone for this purpose.
 

Amylin is a protein synthesized and excreted by specific pancreatic and gastrointestinal cells. This hormone participates in glucose constant level control and in calcium metabolism and hampers gastric motor activity. Recently the scientists have found that this hormone can treat ulcer.
 

Why does stress lead to ulcer development? Strong emotional stress activates one of the immune system components – mast cells, which creep through the organism. Excited mast cells shed histamine, which, among other things, damages mucous stomach coat and it’s only a step to ulcer. Moscow scientists have suggested that amylin somehow affects mast cell activity and started experiments to prove their hypothesis.
 

The physiologists have performed the experiment on rats. The animals were made to suffer an emotional stress, then they were decapitated and their mucous stomach coat was examined.
 

Stress in fact activates mast cells. Dormant cells and cells, which already excreted histamine, are clearly seen by means of the microscope. The more histamine-free cells are observed, the more damaged is the mucous coat of the stomach, which can even bear small hemorrhages. But if amylin is injected intraperitoneally an hour before the stress, mast cells do not respond to the stress, and the average ulcer area reduces two-fold. Thus the researchers made sure that amylin inhibits histamine excretion. Further experiments confirmed protein affecting mast cells directly. The scientists added amylin drop by drop directly to cell culture and detected inhibition of activating agents. Amylin has another useful option: it doesn’t hamper mast cells’ background activity, thus won’t inhibit an important part of immune system.
 

Scientists do not report their further plans. May be someone else uses this data to help people. There’s no need to annoy patients for clinical trials – there’s always more that enough people who suffer from stresses.
 


Tags: Russian medicine     

Next Previous

You might also find interesting:

Metabolic Portraits Novosibirsk Scientists Grew Up Best Material for Flexible Computer Displays Antibiotics: Life Goes On PCR Versus Tuberculosis Students Found Treasures









Comment on our site


RSS   twitter      submit



TAGS:
Tourism Forum  Russian business  Artur Fonvizin  Russian scientists  Cities of Russia  St. Petersburg  Mamonovo  Sochi Games   Russian Proverbs and Sayings  Mercedes-Benz Fashion Week Russia  Archaelogical Finds   Russian fairy tails  Russian Lakes  St. Petersburg Museums  poll  Olympic Games 2012  Internet  Astrakhan Region  Hermitage Museum  award  Russian Poetry  Skolkovo  Russian economy  Russian tourism  Ski resorts  Olympics 2012  Exhibitions in St. Petersburg  Moscow State Theatre of Operetta  Moscow  traffic in Moscow  Nobel Prize  Nikolai Klyuev  Russian Cinema  Ufa  Doll Exhibition  Mireille Mathieu  Helicopter  Russian philosophers  ROSCOSMOS  Ukraine  Gourmet Tours  Nikolai Tokarev  SPIEF 2014  Russian science  Chelyabinsk Region  Alexey Kudrin  Exhibitions in Moscow  Sochi 2014  Chelyabinsk meteorite  Lomonosov 


Travel Blogs
Top Traveling Sites