Add to favorite
 
123
Subscribe to our Newsletters Subscribe to our Newsletters Get Daily Updates RSS


Have a Cocktail Without Harming Your Health
June 26, 2007 23:19


Say NO to beer

On the one hand, alcohol-containing drinks damage cardio-vascular system, but on the other – a glass of red wine is ambrosia for heart. Should people drink alcohol, or not, and what to do when so many tasty drinks surround you?

Medics from Tomsk Science-and-Research Institute of Medical Genetics have found that some genes, responsible for ethanol utilization, affect blood pressure and lipid metabolism, thus increasing chances of coronary atherosclerosis appearing in Western Siberia ihnabitants. However, this relationship doesn’t mean that genes’ effect on cardio-vascular system has direct relations with ethanol metabolism.

 

For many years medic professionals considered drink abuse to cause various cardiovascular diseases. However, recent research result in data, showing opposite effect of moderate drinking, like preventing said diseases, especially coronary heart disease. In fact, ethanol raises blood pressure, concentration of fatty acids and urea in blood, but at the same time it lowers cholesterol content, eliminates blood proteins’ ability to coagulate and clot formation. Ethanol’s effect depends on its concentration in blood – about 90% of alcohol are converted inside liver by means of several enzymes: alcohol dehydrogenase, acetaldehyde dehydrogenase, cytochrome P450 of E21 class and others.

Variations in gene sequences, coding said enzymes, or genetic polymorphism in other words, is that key factor, which influences rate of ethanol degradation and diseases, caused by drinking too much alcohol, as well as genetic disposition to cardio-vascular diseases. Male Japanese, for example, have several certain mutations in genes, coding alcohol dehydrogenase, which allow oxidizing ethanol 100-200 times faster than Europeans do. That is why polymorphism of genes, participating in ethanol degradation, is expected to affect cardiovascular system.

 

Geneticists from Tomsk have examined a group of patients with “ischemic heart disease and coronary atherosclerosis” diagnosis, having almost healthy Tomsk dwellers as a control. All experiment participants allowed analyzing their cardiovascular system and polymorphism of two genes of alcohol dehydrogenase (ADH1B and ADH7) and cytochrome YP21. Scientists successfully discovered mutant variants of said genes, which affect blood pressure, concentration of fatty acids and lipoproteins. Same genes determine rate of ethanol degradation, however researchers consider effect of said genes’ polymorphism on lipid methabolism and blood pressure not to be linked with ethanol degradation function. Possible explanation is that enzymes, which functions are determined by mentioned genes, are responsible for several operations. However, scientists still hope that these genes can be used as alcohol addiction markers.

Nevertheless, the question about mutations, which allow drinking more alcohol without any hazardous consequences, is still open, however scientists recommend abstinence while waiting for scientifically grounded result of their study.

Sources:
    Russian Science News
Kizilova Anna


Tags: Russian scientists Russian science health Tomsk  

Next Previous

You might also find interesting:

New Smartphone By Taiga Systems Unbidden Guests of the Black Sea Russia and France will Co-Develop Technologies for Promising Aircraft Engines New Potentially Dangerous Substances Revealed in Moscow Environment How to Predict Tornadoes?









Comment on our site


RSS   twitter      submit



TAGS:
Moscow  Ski resorts  Google   Krasnodar Territory  RIA Novosti  Olympic Games 2012  Pskov  Alexaner Bubnov  Moscow Spring  Art Fairs  Russian business  Russian Lakes  Multimedia  Daniil Kvyat  Unusual Monuments  Berdsk  tourism  Fashion Futurum  Adler  State Film Fund  Ryazan Kremlin  South Stream  Catherine II  Russian Cinema  Animation Festivals  Leonid Mikhelson  Anomalies  Russian dissidents  hospitality sector in Russia  Russian companies  Central Bank  Exhibitions in Moscow  Russian social networks  Kholmogorye  Peterhof  Russian lifehacks  Russian economy  Dmitry Kardovsky  Chaliapin Opera Festival   St. Petersburg  Moscow Metro  Russian pharmacies  Spacecrafts  Mercedes-Benz Fashion Week Russia  Russian scientists  Folk Arts  Russian tourism  Russian science  FIFA Russia 2018  Tver 


Travel Blogs
Top Traveling Sites