Russian scientists have created a bioartificial liver based on cellular technologies. As a result of its transplantation the functions of a damaged liver may be almost completely restored, as the Head of the Department of the “Federal Research Centre Named after the Academician V.I. Shumakov” Murat Shagidulin said at the first All-Russian Symposium “The newest cellular technologies in medicine” held in Novosibirsk on Wednesday.

      “A cell-engineering construction (CEC) - bioartificial liver – is created on the basis of bone marrow and liver and special matrices (materials that help to restore the tissue in the human body on the introduction of implants, as well as make it possible to grow new organs – notes of ITAR-TASS) which is later implanted in the liver tissue or the mesentry of small intestine. Its introduction into the organism makes liver cells regenerate” - the scientist explained. Preclinical tests were conducted on laboratory animals with triggered acute or chronic liver failure.

      A year after CEC introduction none of the animals died, while mortality in the control group reached 50%. A week after the transplantation the biochemical indicators of the liver function in experimental animals returned to normal.